1. Download Process Explorer from its homepage here: Process Explorer

2. Extract the ZIP file contents to a folder of your choosing. If you don’t have a 3rd party Zip program (I recommend 7-Zip!) you can use Windows’ built-in one: right click the Zip file and select “Extract all…”

3. Double-click the file procexp.exe

4. Enable “Check VirusTotal.com”

The new column VirusTotal will be added automatically, and initially show “Hash submitted…”. After a few seconds it will show the results

5. Processes that are running as System and not as a standard user won’t show a VirusTotal result until Process Explorer is restarted with elevated permissions

You may see a UAC prompt here… click Yes. After a few seconds, we will see the VirusTotal result for every process:

A VirusTotal result of 0/55 means that 55 anti-virus products have checked the file and that non of them have detected anything awry!

Click the result/link to open the detailed report in a web browser. There you’ll find when the scan was done and other useful information like what anti-virus products detected anything and what type of possible infection/malware.

Example of a VirusTotal detection:

   Note If only one AV detected something chances are that it’s a “false positive” (wrongly detected) and that the file is clean. Click the VirusTotal link to get more details about it. 6. If you have processes that show “Unknown” in the VirusTotal column, it means that specific file and version has never been uploaded to VirusTotal. To automatically upload these files to VirusTotal select this option:

7. To submit a file to VirusTotal manually, any file (not only “Unknown” ones), which means to upload and re-scan the file, double click a process, go to the Image tab and click the button below named “Submit”

You can then exit the Properties window and wait until you see a result in the VirusTotal column for that process. It’ll take a few minutes.
8. You can also do a VirusTotal check for all the DLL files a process uses. Select a process and press Ctrl+L to toggle the lower pane. It will submit the file hashes to VirusTotal and show the result after a few seconds:

If you find more than one suspicious process and want to terminate them, it’s recommended by Mark Russinovich, the father of Process Explorer, to first suspend (via right click menu) them. As the vast majority of malware infections include multiple processes that can easily restart each other when a single one is killed, suspending first is a much safer way.